Htaccess set subdomain name?

suddenly encountered a thorny problem. . .
suppose there is a xxx.com/blog
I am using htaccess to rewrite
RewriteRule ^ blog$ src/blog.php
and then I think of a question:
suppose I want to set a subdomain name?
I want him to read the php file in the path app/index.php
when reading shop.xxx.com
. Is that possible? Or can it be done in other ways?


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