according to some tutorials on the Internet, upgrade the openssl version. After the upgrade is complete, use the  openssl version  command to view the version and display 
OpenSSL 1.1.1  11 Sep 2018 this is correct, but use  rpm-qa | grep-I openssl , and display 
openssl-devel-1.0.1e-57.el6.x86_64
openssl-1.0.1e-57.el6.x86_64
pyOpenSSL-0.13.1-2.el6.x86_64is still 1.0.1, I am a little confused, what should I do? Call for help
